Introduction
The JMS-S3000 SpiralTOF™-plus 3.0 is a Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometer (MALDI-TOFMS). It utilizes innovative SpiralTOF ion optics to extend mass range and resolution. This system sets a new standard in MALDI-TOFMS performance for research in synthetic polymers, materials science, and biomolecules.
Product Overview
This system overcomes the ion packet divergence issue of traditional TOFMS by using “Perfect focusing” and a figure-eight trajectory. This allows the JMS-S3000 SpiralTOF™-plus 3.0 to achieve ultra-high mass resolution and mass accuracy even over a long flight distance. It minimizes the topographic effect of matrix crystals, ensuring high reproducibility. With a 14-bit ADC, it provides a wide dynamic range, enabling simultaneous detection of peaks with vastly different intensities. TOF-TOF and Linear TOF options expand capabilities for structural and molecular weight analysis.
Key Features
- SpiralTOF Ion Optics: Achieves ultra-high mass resolution and accuracy via an extended spiral flight path.
- Wide Dynamic Range: Uses a 14-bit ADC to detect major and trace components simultaneously (up to 4 orders of magnitude).
- Reduced Topographic Effect: Maintains high resolution even on uneven sample surfaces, ideal for Imaging MS.
- TOF-TOF Option: Enables detailed structural analysis through high-energy collision-induced dissociation (HE-CID).
- Linear TOF Option: Suitable for determining molecular weight distribution of polymers and intact proteins.
- Dedicated Software: Supports polymer analysis (msRepeatFinder) and imaging analysis (msMicroImager).
Technical Specifications
| Model | JMS-S3000 SpiralTOF™-plus 3.0 |
| Type | MALDI-TOFMS |
| Optical System | SpiralTOF (figure-eight trajectory) |
| Mass Resolution | Ultra-high |
| Dynamic Range | 4 orders of magnitude (14-bit ADC) |
| Options | TOF-TOF, Linear TOF, Imaging MS |
Applications
- Structural and end-group analysis of synthetic polymers.
- Amino acid sequencing of peptides and proteins.
- Mass spectrometry imaging of biological tissues and materials.
- Analysis of lipids, pharmaceuticals, and small molecules.
- Accurate mass measurement of synthetic organic compounds.
Pricing
Please contact us for consultation and detailed quotation.
FAQ
1. How does the JMS-S3000 SpiralTOF™-plus 3.0 differ from conventional MALDI-TOFMS?
It uses SpiralTOF ion optics with a much longer flight path (approx. 17m), resulting in significantly higher mass resolution and accuracy compared to traditional reflectron systems.
2. What is the TOF-TOF option used for?
This option enables high-energy MS/MS (HE-CID), providing detailed structural information, which is very useful for peptide sequencing or polymer structural analysis.
3. Is the instrument suitable for polymer analysis?
Yes, it is one of the instrument’s strongest applications. Combined with msRepeatFinder software, it can analyze polymers, end groups, and molecular weight distributions in detail.
4. How is its Mass Spectrometry Imaging capability?
Due to its high mass resolution and ability to minimize the effect of uneven sample surfaces, it is ideal for imaging, clearly distinguishing substances with close masses on tissue samples.
5. What is the purpose of the Linear TOF mode?
This mode allows for the detection of post-source decay (PSD) ions and high molecular weight molecules (like intact proteins) with high sensitivity, complementing the SpiralTOF mode.
Conclusion
The JMS-S3000 SpiralTOF™-plus 3.0 is the premier MALDI-TOFMS solution for research requiring the highest precision and resolution. Its wide range of applications from materials to biology makes it an indispensable tool in advanced laboratories.
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