The LP and P bioreactor series

The LP and P bioreactor series is based on the same platform concept as NLF. Only bigger. And indeed exactly as big as your production will be. For these bioreactors and fermentors are very easily scalable and offer, even with small production quantities, the possibility of becoming much larger. Let’s grow!

Highlights

• Hi-tech bioreactors for bacteria, yeasts, animal and plant cells
• All Bioengineering production components are also available for the laboratory/pilot benchmark
• For upscaling studies, clinical production and small-batch production – Complete GMP documentation available

Features

• Swift and simple installation: Central connections for steam, water and air minimize time and work requirements while starting operation
• The belt drive reduces the vessel height and provides convenient access to the lid for all work
• Options for cell culture: Rotor filter for perfusion, bubble-free gassing for shear-sensitive cells, empty sterilization for heat-instable media, cell-free sampling system, etc.
• Options for bacteria fermentation: Stirrer systems for bacteria with high oxygen requirement, weight regulation for continuous cultivation, Hi-containment sampling system, etc.
• Can be equipped as a laboratory fermentor in manual operation, or as a production bioreactor in fully-automated operation.
• Controllable with local regulators, BioSCADA or PLC

Technical Details

• Processing capacity: 28 / 33 / 50 / 65 / 100 / 130 / 200 / 300 / 500 / 650 liters
• Vessel: Stainless steel, double shell, double floor
• Drive: Bottom drive with belt, double axial face seal, magnetic drive, top drive
• Stirrers: Rushton, propeller stirrers, pitched-blade stirrers, Vibromixer
• Gassing: Auto-sterile filters, separate filters or double filters. Ring sparger, sinter sparger, surface gassing, bubble-free gassing. Up to 8 gassing lines with pulsed valves or mass-flow controllers.
• Temperature circuit and sterilization: Steam heating / Cooling water. Automated sterilization, empty sterilization.
• Dosing / Transfer: Manual dosing, SteriCaps, transfer concepts, full valve automation. Up to 6 pump module selectable.
• Measurement and control technology: Speed, temperature, pH, pO2, antifoam/level, redox, OD, weight, exhaust-gas analysis. Several interfaces and regulators available for external devices/equipment.
• BioSCADA: Process monitoring, data management, documentation, batch reports, profiles, cascades, sequencer program. Intuitive operation, no programming skills required.