Introduction
The ERD-03 Reciprocating Dissolution Tester is a device for testing drug release from various dosage forms. It complies with USP Apparatus 3 and 7 standards. This tester is ideal for extended-release products that require dissolution profiling at different pH levels. The reciprocating action moves samples through different rows of media, simulating gastrointestinal transit.
Product Overview
This apparatus is designed to automate the testing of extended-release formulations. The ERD-03 features a touch screen for easy programming of up to 20 protocols. Its ability to move samples through six rows of vessels with different media allows it to mimic the changing pH environments of the digestive system. The dip rate, hold time, and drain time are all programmable for each row, providing high flexibility for complex test profiles. This makes the tester a valuable tool for R&D labs.
Key Features
- USP 3/7 Compliant: Complies with USP Apparatus 3 and 7 specifications.
- Programmable Dip Rate: Rate from 5 to 50 dips per minute (dpm).
- Multiple Media Rows: Six rows of vessels for automated pH profile testing.
- Touch Screen Interface: User-friendly operation via a graphical touch screen.
- Protocol Storage: Stores up to 20 programmable protocols with 24 sample intervals.
- Network Connectivity: PC and LAN connectivity for centralized data management.
Technical Specifications
| Model | ERD-03 |
| No. of rows | 6 |
| Vessel capacity | 300 ml (standard) |
| Dip rate (dpm) | 5 to 50 |
| Temperature range | 20°C to 40°C |
| Temperature accuracy | ±0.2°C |
| Display | Touch screen |
| Dimension (L X W X H) | 795 X 675 X 780 mm |
Applications
- Testing of extended-release tablets and capsules.
- Release profiling of drugs at multiple pH levels.
- Simulating in-vivo transit conditions of the GI tract.
- Dissolution testing of transdermal patches (USP 7).
- Testing of non-disintegrating dosage forms.
Pricing
Please contact us for consultation and detailed quotation.
Frequently Asked Questions (FAQ)
1. What is the ERD-03 Reciprocating Dissolution Tester used for?
It is used to test the dissolution rate of extended-release and other dosage forms by reciprocating them through different rows of media, as specified in USP Apparatus 3 and 7.
2. How does this tester simulate the digestive system?
By moving the samples through up to six rows of vessels, each containing media of a different pH, it mimics the journey of a drug through the stomach and intestines.
3. Is the ERD-03 compliant with pharmacopeial standards?
Yes, it complies with the current specifications for USP Apparatus 3 (Reciprocating Cylinder) and USP Apparatus 7 (Reciprocating Holder).
4. What is the dip rate range of the apparatus?
The dip rate is programmable and ranges from 5 to 50 dips per minute (dpm) with an accuracy of ±1%.
5. Can I use different vessel sizes with this instrument?
Yes, optional accessories are available for using 100 ml and 1000 ml vessels in addition to the standard 300 ml vessels.
Conclusion
The ERD-03 Reciprocating Dissolution Tester offers a flexible and compliant solution for complex dissolution profiles. Its ability to automate pH changes makes it essential for developing extended-release products. Contact us for more details.
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