NLF – At a glance

The NLF is a bioreactor for small production volumes. The mobile unit is extremely reliable and space saving and is designed in a modular way. Available inclusive of the GMP documentation packet. Consequently it can be used for low-budget or high-budget production quantities. Or in a nutshell: a super product for your pilot production.

Highlights

• Several automation levels available
• Matched system design; optimal for scale-up and scale-down studies
• Designed according to FDA and GMP Standard

Features

• Individually combinable optional components for special applications and organisms
• Automated sterilization (SIP) and cleaning (CIP)
• Ideal for scale-up and scale-down testing due to matched system design
• Also available as a single fermentor, in multi configuration or as part of the inoculation of a production plant
• Complete documentation according to FDA/EMA Regulations for preclinical applications available.
• Built with robust, long-lasting components – based on 45 years of experience

Technical Details

• Processing capacity: 11 / 13 / 20 liters
• Vessel: Stainless steel, double shell, double floor
• Drives: Top drive, bottom drive, Vibromixer
• Stirrers: Rushton, propeller stirrers, pitched-blade stirrers
• Ventilation: Venting pipe, ring sparger, sinter sparger, surface gassing, bubble-free gassing Temperature circuit and sterilization: Electrical heating / Cooling water, steam heating / Cooling water
• Measurement and control technology: Speed, temperature, pH, pO2, antifoam/level, redox, OD, weight, exhaust analysis, numerous interfaces and regulators
• Gas modules: Up to 8 individual gassing lines with pulsed valves or mass-flow controllers
• Pump modules: Up to 6 pumps
• Cleaning:  Manually / CIP
• BioSCADA: Sophisticated control and visualization software for data collection
• Configuration: Up to 6 bioreactors controllable with a single control unit