EF-2L (Fritus) friability tester: Automated, intelligent, and compliant

Friability is a critical quality attribute that reflects the mechanical strength of a tablet when subjected to physical stress. The EF-2L (Fritus model) friability tester is a new-generation instrument, engineered with a “Quality by Design” philosophy, that combines automation, high-level security, and strict compliance with pharmacopeial standards.

With its ability to connect to a balance, perform automatic calculations, and offer advanced security features like biometric login, the EF-2L (Fritus) is the perfect solution for modern pharmaceutical laboratories that demand high efficiency and data integrity.

Key features of the EF-2L (Fritus) friability tester

This instrument integrates a host of intelligent features to optimize workflows and ensure reliable results.

• Automation and efficiency:

  • Balance connectivity and auto-calculation: The machine can connect directly to an analytical balance via its RS-232 port to automatically calculate the percentage of friability.

  • Smart sample loading and discharge: Allows samples to be loaded into the drum without removing it from the instrument. After the test, samples are automatically discharged.

• Compliant and convenient design:

  • USP compliant: The drum is designed with a 10° tilt, meeting the requirements of the Pharmacopeia.

  • Snap-lock™ mechanism: Makes attaching, detaching, and cleaning the drums quick and easy.

  • cGMP body: The design complies with Good Manufacturing Practice regulations.

• High-level security and data management:

  • Biometric login: Optional fingerprint login for enhanced security.

  • Multi-level security: Allows for the creation of multiple user levels with different access rights.

  • Electronic logbook and audit trail: Provides full Electronic Logbook and Audit Trail capabilities, ready for data integrity requirements.

• Modern interface: A 5-inch TFT touch screen combined with an alphanumeric keypad makes setup and operation intuitive.

Detailed specifications

Frequently asked questions (FAQ)

H3: What is tablet friability and why is it important?

Friability is a measure of a tablet’s tendency to chip, crumble, or break under mechanical stress during packaging, transportation, and handling. A tablet with good mechanical strength (low friability) ensures accurate dosage and maintains its aesthetic appearance.

H3: What is special about the design of the EF-2L (Fritus)?

The most special feature is the front-loading mechanism that allows sample loading without removing the drum, and the ability to automatically discharge the samples after completion. This significantly saves time and effort for the operator and reduces the risk of dropping and breaking the drums.

H3: What is the relationship between the names EF-2L and Fritus?

EF-2L is the name of this friability tester series, while Fritus is the specific model name listed in the specifications and ordering information. Essentially, they refer to the same product.

H3: Does the instrument comply with Pharmacopeia (USP) regulations?

Yes, the instrument is designed to comply with USP requirements, particularly the regulation that the drum must tilt at a 10° angle during the test to create a complex path for the tablets.